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NPRL2 Polyclonal Antibody, 100ul Cell Culture Dishes It may be involved in

SKU: 12465875002

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NPRL2 Polyclonal Antibody, 100ul Cell Culture Dishes It may be involved inSuppresses Src dependent tyrosine phosphorylation and activation of PDPK1 and its downstream signaling. Down regulates PDPK1 kinase activity by interfering with tyrosine phosphorylation at the Tyr 9 Tyr 373 and Tyr 376 residues. May act as a tumor suppressor. Suppresses cell growth and enhanced sensitivity to various anticancer drugs.

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Description

It may be involved in eye and cerebellum development| and it has been proposed that expansion of a trinucleotide repeat region in the 5' UTR may play a role in a variety of psychiatric disorders

Oligomerization results from formation of a five-stranded coiled coil and disulfides

with a strong preference for the latter

This protein is a member of the ALD subfamily| which is involved in peroxisomal import of fatty acids and/or fatty acyl-CoAs in the organelle

which is abundant in the eukaryotic cytosol and may be involved in the transport and assembly of newly synthesized proteins

NPRL2 Polyclonal Antibody, 100ul Cell Culture Dishes It may be involved inSuppresses Src dependent tyrosine phosphorylation and activation of PDPK1 and its downstream signaling. Down regulates PDPK1 kinase activity by interfering with tyrosine phosphorylation at the Tyr 9 Tyr 373 and Tyr 376 residues. May act as a tumor suppressor. Suppresses cell growth and enhanced sensitivity to various anticancer drugs.

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