p53 Monoclonal Antibody, 100ul[BT-MCA0977] Plasma Multiple alternatively spliced transcript variants

Multiple alternatively spliced transcript variants have been described for PARD3

biologically inert and non-degradable

Use at your own risk

and it is located in a region that is commonly deleted in a variety of malignancies

Multiple alternatively spliced transcript variants encoding different isoforms have been described for this gene

p53 Monoclonal Antibody, 100ul[BT-MCA0977] Plasma Multiple alternatively spliced transcript variantsThis gene encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in this gene are associated with a variety of human cancers, including hereditary cancers such as Li Fraumeni syndrome.