SIR4 Polyclonal Antibody, 100ul Nucleic Acid Amplification Mutations in this gene may

Mutations in this gene may be associated with male infertility and premature ovarian failure in female human patients

Acyl-coenzyme A thioesterase 4 is an enzyme encoded by the ACOT4 gene in humans and is mapped to chromosome 14

These proteins are basic helix-loop-helix transcription factors which can act as tumor suppressors but lack DNA binding activity

Heterozygous loss-of-function mutations in KLF1 result in the dominant In (Lu) blood phenotype

in particular

SIR4 Polyclonal Antibody, 100ul Nucleic Acid Amplification Mutations in this gene mayThis gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular