LXR-623 5363 Chemical Name: hexasodium (1R

Chemical Name: hexasodium (1R

structural determination and biological activities

0 µM PND-1186 (>5-fold above IC50) had limited effects on cell proliferation

CAS Number: 1397255-09-2

Afuresertib hydrochloride

LXR-623 5363 Chemical Name: hexasodium (1RLXR623, also known as WAY 252623, is a highly selective and orally bioavailable synthetic modulator of LXR, which demonstrated efficacy for reducing lesion progression in the murine LDLR( ) atherosclerosis model with no associated increase in hepatic lipogenesis either in this model or Syrian hamsters. In nonhuman primates with normal lipid levels, WAY 252623 significantly reduced total (50 55%) and LDL cholesterol (LDLc) (70 77%) in a time and dose