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Verosudil - CAS# 1414854-42-4 Catalog No.:M6847-2 US 20160039756 A1

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Verosudil - CAS# 1414854-42-4 Catalog No.:M6847-2 US 20160039756 A1Verosudil, CAS No. 1414854 42 4, also known as AR 12286, is a potent and selective Rho kinase inhibitor. AR 12286 was well tolerated and provided statistically significant reduction in IOP (intraocular pressure) in patients with XFS (exfoliation syndrome) and OHT (ocular hypertension) or XFG (exfoliative glaucoma). This drug may represent an additional therapeutic paradigm for the treatment of XFG. Product information CAS Number: 1414854 42 4

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US 20160039756 A1

Pyridone 6

2016 May 12

and this increase is significantly attenuated by Pirfenidone administration on day 28 after BLM treatment (P=0

84(2):110-5

Verosudil - CAS# 1414854-42-4 Catalog No.:M6847-2 US 20160039756 A1Verosudil, CAS No. 1414854 42 4, also known as AR 12286, is a potent and selective Rho kinase inhibitor. AR 12286 was well tolerated and provided statistically significant reduction in IOP (intraocular pressure) in patients with XFS (exfoliation syndrome) and OHT (ocular hypertension) or XFG (exfoliative glaucoma). This drug may represent an additional therapeutic paradigm for the treatment of XFG. Product information CAS Number: 1414854 42 4

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