MK-8033 Size:Solid 2 mg is a potent and competitive

is a potent and competitive AMPA/kainate receptor antagonist with IC50s of 0

InChi: InChI=1S/C26H27N3O4S/c30-25-17-33-26(18-29(25)22-7-8-22)11-14-28(15-12-26)34(31

2019 Jun 20

As a selective antagonist of the endothelin-A (ETA) receptor

50(2):355-67

MK-8033 Size:Solid 2 mg is a potent and competitiveMK8033 is a selective small molecule inhibitor, ATP competitive. Phase I investigation of the cMet inhibitor MK 8033 is ongoing. Plans include a trial of this agent in refractory colorectal cancer, with pre and post treatment biopsies to evaluate for relevant molecular signatures. Product information CAS Number: 1001917 37 8 Molecular Weight: 471. 53 Formula: C25H21N5O3S Synonym: MK 8033 MK 8033 MK8033 Chemical Name: 1 [5 (1 methyl 1H pyrazol 4 yl) 2