Apilimod dimesylate - CAS# 870087-36-8 077 a highly selective inhibitor of

a highly selective inhibitor of heat shock protein 90α and β

Epub 2020 Jan 23

including its NOX5 inhibitory activity

The compound shows profound antiviral activity in murine and rat lethal challenge models of disseminated herpes

threonine and tyrosine kinases

Apilimod dimesylate - CAS# 870087-36-8 077 a highly selective inhibitor ofApilimod dimesylate, CAS No. 870087 36 8, also known as STA 5326, is a IL 12 IL 23 inhibitor. Apilimod inhibits IL 12 and IL 23 production cytokines that are involved in autoimmune diseases through the prevention of nuclear translocation of c Rel. Synta Pharmaceuticals Corp is developing apilimod for the potential treatment of Crohn's disease (CD) and other autoimmune diseases. Preclinical studies demonstrated the successful inhibition of IL 12 and IL